WebCompelling evidence shows that brown and beige adipose tissue are protective against metabolic diseases. PR domain-containing 16 (PRDM16) is a dominant activator of the biogenesis of beige adipocytes by forming a complex with transcriptional and epigenetic factors and is therefore an attractive target for improving metabolic health. WebTranslational Control. The control of gene expression can also utilize translational mechanisms. These mechanisms are usually directed at initiation. For example, in response to virus challenge, the protein interferon is released and turns off protein synthesis in neighboring cells by a dual mechanism. First, interferon induces mRNA degradation.
Post-translational control of beige fat biogenesis by …
WebThere are three general types of adipose tissue: white, brown, and brown-in-white or “beige” fat. All three types of adipose tissue communicate extensively with other organs in the body, including skin, liver, pancreas, muscle, and brain, to maintain energy homeostasis. WebThere are three general types of adipose tissue: white, brown, and brown-in-white or “beige” fat. All three types of adipose tissue communicate extensively with other organs in the … churchlands high school fees
EconPapers: Post-translational control of beige fat biogenesis by ...
Web10 Aug 2024 · The study revealed the mechanism through which cytokines — immune cell signaling molecules — promote the production of beige fat, thus reducing obesity and other metabolic disorders ... Web12 Oct 2024 · Beige fat arises from white fat (precursors or mature cells). ... Histones are subject to various post-translational modifications such as acetylation, methylation, phosphorylation, and ubiquitination and thus contribute to the regulation of chromatin states and transcriptional activities. ... (GLP-1) may control energy metabolism through its ... Webof a distinct beige fat cell precursor, and (iii) differentiation frombrown orwhite adipocyte precursors[17, 60, 61].Itwas previously suggested that browning is a feature of WAT in-stead of beige adipocytes being a distinct cell type, but this theory was heavily questioned by the findings on beige adi-pocyte gene expression pattern by Wu et al ... churchlands high school uniform shop