Phospho1 gene

Author: pexb

August undefined, 2024

WebHere we identify phosphatase orphan 1 (Phospho1) as a new player in myogenesis. During activation, proliferation, and differentiation of quiescent satellite cells, the expression of Phospho1 gradually increases. Overexpression of Phospho1 inhibits myoblast proliferation but promotes their differentiation and fusion. WebZFIN Gene: phospho1 Gene phospho1 ID ZDB-GENE-040801-198 Name phosphoethanolamine/phosphocholine phosphatase 1 Symbol phospho1 Nomenclature History Previous Names sb:cb839 zgc:92423 ( 1) Type protein_coding_gene Location Chr: 3 Mapping Details/Browsers Description Predicted to have phosphatase activity.

ZFIN Gene: phospho1

WebABSTRACTHypophosphatasia (HP) is an inherited disorder characterized by defective bone and teeth mineralization and deficiency of serum and bone alkaline phosphatase (AP) activity. For severe forms, disease frequency has been estimated at 1/100,000. WebApr 10, 2024 · Prostate cancer (PCa) is the second most common cause of cancer death in American men. Metastatic castration-resistant prostate cancer (mCRPC) is the most lethal form of PCa and preferentially metastasizes to the bones through incompletely understood molecular mechanisms. Herein, we processed RNA sequencing data from patients with … how many calories in a chocolate paddle pop

PHOSPHO1 protein expression summary - The Human Protein Atlas

WebPHOSPHO1 is a highly conservative gene with homologs across multiple species. Human-derived, chicken-derived, and mouse-derived PHOSPHO1 genes showed conserved … WebOct 22, 2024 · This study identifies PHOSPHO1 as a potential bone-derived therapeutic target for the treatment of obesity and diabetes. We show that mice lacking the bone … WebMar 21, 2024 · PHOSPHO1 (Phosphoethanolamine/Phosphocholine Phosphatase 1) is a Protein Coding gene. Diseases associated with PHOSPHO1 include Periarthritis and Hypophosphatasia, Childhood . Among its related pathways are Glycerophospholipid … ACHE (Acetylcholinesterase (Cartwright Blood Group)) is a Protein Coding gene. … CD200R1 (CD200 Receptor 1) is a Protein Coding gene. Diseases associated with … PGAM1 (Phosphoglycerate Mutase 1) is a Protein Coding gene. Diseases … high res winston-salem photography historic

PHOSPHO1 Serves as a Key Metabolism-Related …

Transcriptome Analysis Identifies Tumor Immune …

WebCerebral cortex Cerebellum Choroid plexus Basal ganglia Thalamus Hypothalamus Midbrain Pons Medulla oblongata Hippocampal formation Spinal cord White matter Amygdala Retina Thyroid gland Parathyroid gland Adrenal gland Pituitary gland Lung Salivary gland Esophagus Tongue Stomach Duodenum Small intestine Colon Rectum Liver Gallbladder … WebJun 28, 2024 · Among these genes, PHOSPHO1 is the only one directly related to PC metabolism. We thus examined PHOSPHO1 messenger RNA (mRNA) expression by real-time quantitative reverse transcription PCR to confirm the temporal increase of PHOSPHO1 expression during terminal erythropoiesis (Figure 1E ). how many calories in a chocolate crepeWebOct 22, 2024 · Gene and protein expression of Phospho1 mRNA and PHOSPHO1 protein in murine tissue (a) RT-qPCR of Phospho1 in murine tissues, high expression was seen in … how many calories in a chocolate cookie

"WebDec 20, 2024 · Phospho1-R74X-null mutant mice (Phospho1 KO) were generated and maintained as previously described. 31 This strain carries a C>T mutation in codon 74 of exon 2 of the Phospho1 gene leading to a premature stop codon (R74X) and the complete absence of PHOSPHO1 protein. 31 All animal experiments were approved by the Roslin … " - Phospho1 gene

Phospho1 gene

Increased PHOSPHO1 and alkaline phosphatase expression …

WebGene target information for PHOSPHO1. Find diseases associated with this biological target and compounds tested against it in bioassay experiments. WebApr 10, 2024 · Gene and transcript expressions on the GTEx portal are shown in transcripts per million (TPM). ... 10 hub genes (ALPL, PHEX, RUNX2, ENPP1, PHOSPHO1, PTH1R, COL11A1, COL24A1, COL22A1, and COL13A1) ...

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WebJul 20, 2024 · Within the PHOSPHO1 gene, differential methylation sites have been identified as potentially useful biomarkers for clinical application in the early detection of type 2 diabetes [35] and... WebPHOSPHO1. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas …

WebPhospho1 Gene Detail Summary Symbol. Phospho1 Name. phosphatase, orphan 1. Synonyms. D11Moh36 Feature Type. protein coding gene. IDs. MGI:2447348 ... Gene Model ID Feature Type Coordinates Select Strains; C57BL/6J: MGI_C57BL6J_2447348: protein coding gene: Chr11:95715325-95722966 (+) WebEST transcripts from both the human and mouse Phospho1 gene, with a high degree of conservation at both the gene and protein level between these two mammalian species. Chromo-somal mapping led to the conclusion that the Phospho1 gene was indeed conserved between the bird and mouse genomes, located within a region of conserved …

WebGene target information for PHOSPHO1. Find diseases associated with this biological target and compounds tested against it in bioassay experiments. This application requires … WebApr 10, 2024 · Prostate cancer (PCa) is the second most common cause of cancer death in American men. Metastatic castration-resistant prostate cancer (mCRPC) is the most …

WebPHOSPHO1 has 2,767 functional associations with biological entities spanning 8 categories (molecular profile, organism, functional term, phrase or reference, chemical, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 59 datasets.

WebDec 1, 2003 · PHOSPHO1 gene expression has also been detected in the human mineralizing osteoblast‐like cell line, SaOS‐2 (but not in the MG‐63 non‐mineralizing osteoblast‐like cell line) and immunohistochemical staining with anti‐PHOSPHO1 antibody has shown the protein to be present at mineralizing regions in chick bone (Houston et al., … how many calories in a chocolate brownieWebSep 5, 2024 · The cyto-phosphatase PHOSPHO1 generates phosphate from membrane phospholipid C through hydrolyzed phosphocholine and phosphoethanolamine. Type III Na/Pi cotransporter is also given for phosphates both on the cell membrane and on the vesicle matrix membrane. how many calories in a chocolate shakeWebJun 30, 2024 · Treatment of mice with the PHOSPHO1 substrate phosphocholine is sufficient to induce cold tolerance, thermogenic gene expression, and allied metabolic benefits. Our results reveal a role of PHOSPHO1 as a negative regulator of BAT thermogenesis, and inhibition of PHOSPHO1 or enhancement of phosphocholine … how many calories in a chocolate sundaeWebFeb 3, 2024 · Given that the skeletal manifestations of genetic ablation of the Phospho1 gene in mice resemble many of the manifestations of HPP, we propose that Phospho1 … how many calories in a chipwichWebJul 26, 2024 · Common variant gene-level associations for PHOSPHO1 as the closest gene with metabolic disorders indicators. Frontiers in Physiology frontiersin.org 04 Liu et al. 10.3389/fphys.2024.935195 how many calories in a chocolate lime sweetWebOdontohypophosphatasia shows only dental manifestations. To date, 302 mutations in the ALPL gene have been reported, mainly single-nucleotide substitutions, and the relationships between phenotype and genotype have been partially elucidated. ... Pit1 (a sodium–phosphate [Na/Pi] cotransporter), and PHOSPHO1. 28 The first step of the ... high res winter wallpaperWebMay 5, 2024 · Here we show that mice lacking the bone mineralization enzyme PHOSPHO1 (Phospho1-/-) exhibited improved basal glucose homeostasis and resisted high-fat-diet induced weight gain and diabetes.... how many calories in a chicken thigh fried