miRNAs can target HMGB3 to regulate the glycolysis pathway of the tumor under hypoxia. Studies have confirmed that miRNA-758 regulates the Wnt/β-catenin signaling pathway by inhibiting the expression of the HMGB3 and inhibit the proliferation, migration, and invasion of cervical cancer and non … See more With the discovery of research, the abnormal expression of HMGB3 is closely related to the occurrence of many tumors, and HMGB3 is highly expressed in a variety … See more HMGB3 is not only involved in the regulation of tumor occurrence, malignant proliferation, and metastasis but also regulating the occurrence of chemotherapy … See more WebHMGB3 binds to nucleosomes in a sequence-independent manner and participates in DNA repair, replication, transcription, and recombination. HMGB3 is highly expressed in stem cells and cancer cells and is rarely transactivated in normal adult tissues, making it a promising therapeutic target.
High Mobility Group Protein - an overview ScienceDirect Topics
WebThe high mobility group protein B (HMGB) family (including HMGB1, HMGB2, HMGB3, and HMGB4) can regulate the mechanisms of DNA replication, transcription, recombination, … WebThe HMG (high mobility group) proteins are transcription regulators. HMGAs bind to the AT-rich regions of the minor groove of the DNA. HMGA2 is overexpressed in some cancers. It … how to step up dc voltage without transformer
HMGB1 - Wikipedia
WebCharlotte, North Carolina WebHMGB3 (High Mobility Group Box 3 (HMGB3)) Reactivity All reactivities for HMGB3 elisa kits Human Detection Method Colorimetric Method Type Sandwich ELISA Detection Range 0.313 ng/mL - 20 ng/mL Minimum Detection Limit 0.313 ng/mL Application ELISA Purpose For quantitative detection of HMGB3 in serum, plasma, tissue homogenates. Sample Type WebFind a barre3® studio near you or subscribe to barre3 Online and start an online workout today. react shoes