TīmeklisDrug interactions associated with ezetimibe include: Ciclosporin — plasma concentration of both drugs may increase when ezetimibe is given with ciclosporin. Concurrent use should be done cautiously, and ciclosporin concentrations should be monitored. Fibrates — predicted to increase the risk of gallstones when given with … Ezetimibe is a medication used to treat high blood cholesterol and certain other lipid abnormalities. Generally it is used together with dietary changes and a statin. Alone, it is less preferred than a statin. It is taken by mouth. It is also available in the fixed combinations ezetimibe/simvastatin, ezetimibe/atorvastatin, ezetimibe/rosuvastatin, and ezetimibe/bempedoic acid.
Bempedoic Acid for LDL-C Lowering: What Do We Know?
In pharmacology, the fibrates are a class of amphipathic carboxylic acids and esters. They are derivatives of fibric acid (phenoxyisobutyric acid). They are used for a range of metabolic disorders, mainly hypercholesterolemia (high cholesterol), and are therefore hypolipidemic agents. Tīmeklis11 rindas · 2024. gada 10. aug. · Other lipid-lowering agents. CYP3A4 inhibitors. PCSK9 inhibitors (e.g., alirocumab, evolocumab) Add-on therapy for patients who have both … bobtown wv
Second-line lipid-lowering agents - Knowledge @ AMBOSS
Tīmeklis2024. gada 17. febr. · Myopathy: Myopathy, including rhabdomyolysis, has been reported (rarely) with ezetimibe monotherapy; risk may be increased with concomitant use of a statin or fibrate. Discontinue ezetimibe and statin or fibrate immediately if myopathy is suspected or confirmed (symptomatic patient with CPK >10 x ULN). … TīmeklisFibrate. In pharmacology, the fibrates are a class of amphipathic carboxylic acids and esters. They are derivatives of fibric acid (phenoxyisobutyric acid). They are used for a range of metabolic disorders, mainly hypercholesterolemia (high cholesterol ), and are therefore hypolipidemic agents . Tīmeklis2024. gada 1. jūl. · Therefore, we used a fibrate in the present study. The treatment with fenofibrate successfully reduced the serum TG level and increased the HDL-C level. … bob track application status