WebJan 5, 2015 · 5,3′-Dihydroxy-6,7,4′-trimethoxyflavanone (DHTMF) is one of the constituents of Vitex rotundifolia, a medicinal herb that is used for the treatment of various disorders in China and Korea. In this study we evaluated the antitumor and antiangiogeneic activities of DHTMF. DHTMF significantly suppressed growth and induced apoptosis in lung ... WebDHTMF, 1 μmol/L IM +5 μg/mL DHTMF, and 1 μmol/L IM +10 μg/mL DHTMF) for 24, 48, and 72 h, and cell viability was determined by the CCK8 assay. As shown in Figure 3, inhibitory ratio was significantly increased by DHTMF alone and in combination with IM (P<0.01). The inhibitory ratio was greater than 45% when 1 μmol/L

PRIMARY RESEARCH Open Access A polymethoxyflavone …

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